location: Current position: Home >> Scientific Research >> Paper Publications

Fabrication of artificial fluorescent protein probe for HSA recognition and relay sensing Ag+ by functional microenvironment-sensitive fluorescent dye

Hits:

Indexed by:期刊论文

Date of Publication:2018-06-15

Journal:SENSORS AND ACTUATORS B-CHEMICAL

Included Journals:SCIE、EI

Volume:263

Page Number:661-667

ISSN No.:0925-4005

Key Words:Artificial fluorescent protein; Fluorescent recognition; Relay sensing; Silver ion; Nanosensor

Abstract:Green fluorescent protein (GFP) becomes one of the most important imaging tools in biology and biomedicine. To simplify usage, expand the application and avoid complicated operations, a kind of artificial fluorescent protein (AFP) is inspired and fabricated by lighting up human serum albumin (HSA) with loading microenvironment-sensitive fluorescent dye DMAR, which could be applied in HSA assay in human urine and serum samples as a physiological indicator of diagnosis in clinical. Besides, the AFP, DMAR/HSA, could act as a nanosensor for Ag+ sensing with good selectivity by a new relay recognition strategy. (C) 2018 Elsevier B.V. All rights reserved.

Pre One:An estrogen receptor targeted ruthenium complex as a two-photon photodynamic therapy agent for breast cancer cells

Next One:A FRET chemosensor for hypochlorite with large Stokes shifts and long-lifetime emissions