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A near-infrared heptamethine aminocyanine dye with a long-lived excited triplet state for photodynamic therapy

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Indexed by:期刊论文

Date of Publication:2018-08-25

Journal:CHEMICAL COMMUNICATIONS

Included Journals:SCIE

Volume:54

Issue:66

Page Number:9198-9201

ISSN No.:1359-7345

Abstract:A water-soluble near-infrared aminocyanine dye has been developed with a long triplet-state lifetime ( = 9.16 s in deaerated ethanol). Thereby, extremely high singlet oxygen quantum yield (phi = 0.20) and low dark cytotoxicity (IC50 = 715.4 M) were achieved. The potential of the dye as a PDT photosensitizer was demonstrated.

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