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Indexed by:期刊论文

Date of Publication:2007-01-01

Journal:DYES AND PIGMENTS

Included Journals:SCIE、EI

Volume:73

Issue:2

Page Number:206-210

ISSN No.:0143-7208

Key Words:BODIPY; fluorescent dyes; PET; pH probe; biological label

Abstract:New BODIPY dyes have been synthesized via the condensation of R-CH2COCl (R = H, Br, Cl and Et2N) with 2,4-dimethylpyrrole and the coordination with BF3 etherate. The acetyl chlorides with electron-withdrawing substituents (R = Br or Cl) are easier to react with the 2,4-dimethylpyrrole to form the related dyes and make a red-shift in absorbance and fluorescence maximum. Dye 4 (R = Et2N), based on PET mechanism, exhibits good properties as a pH fluorescent sensor with a pK(a) of 8.74 and a 15-fold fluorescence enhancement in the pH range of 9.38-7.60. (c) 2005 Elsevier Ltd. All rights reserved.