Release Time:2019-03-10  Hits:

Indexed by: Journal Article

Date of Publication: 2007-01-01

Journal: DYES AND PIGMENTS

Included Journals: EI、SCIE

Volume: 73

Issue: 2

Page Number: 206-210

ISSN: 0143-7208

Key Words: BODIPY; fluorescent dyes; PET; pH probe; biological label

Abstract: New BODIPY dyes have been synthesized via the condensation of R-CH2COCl (R = H, Br, Cl and Et2N) with 2,4-dimethylpyrrole and the coordination with BF3 etherate. The acetyl chlorides with electron-withdrawing substituents (R = Br or Cl) are easier to react with the 2,4-dimethylpyrrole to form the related dyes and make a red-shift in absorbance and fluorescence maximum. Dye 4 (R = Et2N), based on PET mechanism, exhibits good properties as a pH fluorescent sensor with a pK(a) of 8.74 and a 15-fold fluorescence enhancement in the pH range of 9.38-7.60. (c) 2005 Elsevier Ltd. All rights reserved.