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Indexed by:期刊论文

Date of Publication:2005-08-01

Journal:JOURNAL OF LUMINESCENCE

Included Journals:SCIE、EI、Scopus

Volume:114

Issue:2

Page Number:125-130

ISSN No.:0022-2313

Key Words:zinc ion; 1,8-naphthalimide; fluorescent sensors; PET; fluorescent probe

Abstract:A new Zn2+ fluorescent sensor NIDPA, with 1,8-naphthalimide as reporting group and di-2-picolylamine (DPA) as recognizing group, has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a five-fold fluorescent enhancement and 10nm absorption blue-shift under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (K-d) is 0.83 nM, and Ca2+, Mg2+, Fe2+, Ni2+ and Cr3+ have little influence on fluorescent enhancement. These results suggest that NIDPA can be used to quantitatively and selectively measure the concentration of Zn2+ around sub-nanomolar range. (c) 2005 Elsevier B.V. All rights reserved.