Release Time:2019-03-10  Hits:

Indexed by: Journal Article

Date of Publication: 2005-08-01

Journal: JOURNAL OF LUMINESCENCE

Included Journals: Scopus、EI、SCIE

Volume: 114

Issue: 2

Page Number: 125-130

ISSN: 0022-2313

Key Words: zinc ion; 1,8-naphthalimide; fluorescent sensors; PET; fluorescent probe

Abstract: A new Zn2+ fluorescent sensor NIDPA, with 1,8-naphthalimide as reporting group and di-2-picolylamine (DPA) as recognizing group, has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a five-fold fluorescent enhancement and 10nm absorption blue-shift under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (K-d) is 0.83 nM, and Ca2+, Mg2+, Fe2+, Ni2+ and Cr3+ have little influence on fluorescent enhancement. These results suggest that NIDPA can be used to quantitatively and selectively measure the concentration of Zn2+ around sub-nanomolar range. (c) 2005 Elsevier B.V. All rights reserved.