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A novel fluorescent sensor for triplex DNA

Release Time:2019-03-10  Hits:

Indexed by: Journal Article

Date of Publication: 2005-01-17

Journal: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Included Journals: PubMed、SCIE、Scopus

Volume: 15

Issue: 2

Page Number: 255-257

ISSN: 0960-894X

Key Words: biosensor; triplex DNA; fluorescent

Abstract: A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4-aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T-AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer. (C) 2004 Elsevier Ltd. All rights reserved.

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