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A novel fluorescent sensor for triplex DNA

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Indexed by:期刊论文

Date of Publication:2005-01-17

Journal:BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Included Journals:Scopus、SCIE、PubMed

Volume:15

Issue:2

Page Number:255-257

ISSN No.:0960-894X

Key Words:biosensor; triplex DNA; fluorescent

Abstract:A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4-aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T-AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer. (C) 2004 Elsevier Ltd. All rights reserved.

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