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Indexed by:期刊论文

Date of Publication:2004-10-05

Journal:CHEMISTRY LETTERS

Included Journals:Scopus、SCIE

Volume:33

Issue:10

Page Number:1392-1393

ISSN No.:0366-7022

Abstract:A new Zn2+ fluorescent sensor NIDPA (1) which takes 1,8-naphthalimide as a reporting group and di-2-picolylamine (DPA) as a recognizing group has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a nearly 5-fold fluorescent enhancement under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (K-d) is in the sub-nM range, and Ca2+, Mg2+, Fe3+, Ni2+, and Cr3+ have little influence on fluorescence enhancement.