A Ligand-Free Copper-Catalyzed Decarboxylative Trifluoromethylation of Aryliodides with Sodium Trifluoroacetate Using Ag2O as a Promoter
Release Time:2019-03-09 Hits:
Indexed by: Journal Article
Date of Publication: 2011-07-01
Journal: SYNLETT
Included Journals: SCIE
Issue: 12
Page Number: 1713-1716
ISSN: 0936-5214
Key Words: copper-catalyzed; trifluoromethylation; decarboxylative; silver oxide; cross-coupling
Abstract: A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag2O as a promoter was reported. A variety of trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields and with wide functional-group tolerance under relatively mild reaction conditions.
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