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Indexed by:期刊论文
Date of Publication:2011-07-07
Journal:ORGANIC & BIOMOLECULAR CHEMISTRY
Included Journals:SCIE、EI、PubMed、Scopus
Volume:9
Issue:13
Page Number:4983-4986
ISSN No.:1477-0520
Abstract:A wide range of free N-H 2-arylindoles were synthesised via the copper(II)-catalyzed amination of 2-bromo-arylacetylenes with aqueous ammonia and sequential intramolecular cyclization. The convenience and atom economy of aqueous ammonia, and the low cost of the copper catalytic system make this protocol readily superior in practical application.