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The Inactivation of Resistant Candida Albicans in a Sealed Package by Cold Atmospheric Pressure Plasmas

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-01-01

Journal: PLASMA PROCESSES AND POLYMERS

Included Journals: Scopus、EI、SCIE

Volume: 9

Issue: 1

Page Number: 17-21

ISSN: 1612-8850

Key Words: atmospheric-pressure plasmas; cold plasmas; nonequilibrium plasmas; optical emission spectrum (OES); plasma medicine

Abstract: It remains a challenge to generate cold, atmospheric pressure plasmas in sealed packages for biological disinfection. In this paper, we report a plasma device to form large-area and atmospheric-pressure plasmas in a sealed package for the low-temperature disinfection of fungi. The visually uniform plasmas were easily generated in the portable plastic bag containing Candida albicans with a population of 105 spores placed on the plasma device. The He plasma containing about 1% O2 was found to entirely kill resistant Candida albicans with a treatment time of 5?min. Measurements for optical emission spectra and disinfection efficiencies indicate that the plasma-created species such as O radicals and charged species play a major role in the inactivation process.

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