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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本横滨国立大学
学位：博士
所在单位：化工学院
学科：应用化学. 精细化工. 有机化学
办公地点：大连市高新区凌工路2号大连理工大学西部新区F-412
联系方式：大连市高新区凌工路2号大连理工大学西部新区F-412 邮政编码 116024 电话：0411-84986295 电子信箱：ymli@dlut.edu.cn
电子邮箱：ymli@dlut.edu.cn
Highly efficient Cu(I)-catalyzed trifluoromethylation of aryl(heteroaryl) enol acetates with CF3 radicals derived from CF3SO2Na and TBHP at room temperature
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论文类型：期刊论文
发表时间：2014-05-01
发表刊物：JOURNAL OF FLUORINE CHEMISTRY
收录刊物：SCIE
卷号：161
页面范围：128-133
ISSN号：0022-1139
关键字：Trifluoromethylation; Enol acetates; Synthetic methods; alpha-CF3 ketone; Radical addition
摘要：An efficient method for the Cu(I)-catalyzed synthesis of a-trifluoromethyl ketones via the addition of CF3 to aryl(heteroaryl) enol acetates by using the readily available CF3SO2Na (Langlois reagent) has been developed. The reaction is experimentally simple and carried out at room temperature, providing good to excellent yields with wide functional group tolerance. (C) 2014 Elsevier B.V. All rights reserved.