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论文类型：期刊论文

第一作者：Lu, Yang

通讯作者：Li, YM (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China.

合写作者：Li, Yaming,Zhang, Rong,Jin, Kun,Duan, Chunying

发表时间：2014-05-01

发表刊物：JOURNAL OF FLUORINE CHEMISTRY

收录刊物：SCIE

卷号：161

页面范围：128-133

ISSN号：0022-1139

关键字：Trifluoromethylation; Enol acetates; Synthetic methods; alpha-CF3 ketone; Radical addition

摘要：An efficient method for the Cu(I)-catalyzed synthesis of a-trifluoromethyl ketones via the addition of CF3 to aryl(heteroaryl) enol acetates by using the readily available CF3SO2Na (Langlois reagent) has been developed. The reaction is experimentally simple and carried out at room temperature, providing good to excellent yields with wide functional group tolerance. (C) 2014 Elsevier B.V. All rights reserved.