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发布时间：2019-03-09

论文类型：期刊论文

发表时间：2011-07-01

发表刊物：SYNLETT

收录刊物：SCIE

期号：12

页面范围：1713-1716

ISSN号：0936-5214

关键字：copper-catalyzed; trifluoromethylation; decarboxylative; silver oxide; cross-coupling

摘要：A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag2O as a promoter was reported. A variety of trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields and with wide functional-group tolerance under relatively mild reaction conditions.