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发布时间：2019-03-09

论文类型：期刊论文

发表时间：2011-07-07

发表刊物：ORGANIC & BIOMOLECULAR CHEMISTRY

收录刊物：Scopus、PubMed、EI、SCIE

卷号：9

期号：13

页面范围：4983-4986

ISSN号：1477-0520

摘要：A wide range of free N-H 2-arylindoles were synthesised via the copper(II)-catalyzed amination of 2-bromo-arylacetylenes with aqueous ammonia and sequential intramolecular cyclization. The convenience and atom economy of aqueous ammonia, and the low cost of the copper catalytic system make this protocol readily superior in practical application.