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Ratiometric fluorescent probe for sensing Streptococcus mutans glucosyltransferase, a key factor in the formation of dental caries

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Indexed by:期刊论文

Date of Publication:2021-02-01

Journal:CHEMICAL COMMUNICATIONS

Volume:55

Issue:24

Page Number:3548-3551

ISSN No.:1359-7345

Abstract:We report on a naphthalimide ratiometric fluorescent probe for the real-time sensing and imaging of pathogenic bacterial glucosyltransferases, which are associated with the development of dental caries. Using a high-throughput screening method, we identified that several natural polyphenols from green tea were GTFs inhibitors that could eventually lead to suitable oral treatments to prevent the development of dental caries.

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