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Indexed by:期刊论文

Date of Publication:2012-05-01

Journal:CHEMISTRY OF NATURAL COMPOUNDS

Included Journals:SCIE、Scopus

Volume:48

Issue:2

Page Number:194-197

ISSN No.:0009-3130

Key Words:alkaloid; L-alanine; transesterification; lactone

Abstract:2-(5-Hydroxymethyl-2-formylpyrrol-1-yl)propionic acid lactone was synthesized in six steps with a 17.0% overall yield, starting from L-alanine. The synthetic route involved the Clauson-Kaas reaction, Vilsmeier reaction, and transesterification. The transesterification was the key step in the formation of the target compound.