王静云
个人信息Personal Information
教授
博士生导师
硕士生导师
性别:女
毕业院校:大连理工大学
学位:博士
所在单位:生物工程学院
学科:生物化工. 生物工程与技术. 药物工程
办公地点:生物楼512
联系方式:wangjingyun67@dlut.edu.cn
电子邮箱:wangjingyun67@dlut.edu.cn
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A fluorescent probe for H2S in vivo with fast response and high sensitivity
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论文类型:期刊论文
发表时间:2015-11-21
发表刊物:CHEMICAL COMMUNICATIONS
收录刊物:SCIE、PubMed、Scopus
卷号:51
期号:90
页面范围:16225-16228
ISSN号:1359-7345
摘要:In this work, we design and synthesize a new near-infrared (NIR) ratiometric fluorescent probe FD-H2S for the highly sensitive (DL 68.2 nM) detection of H2S with fast response (15 s), large emission shift (220 nm) and excellent enhancement (168-fold in ratiometric value). The probe could be applied for monitoring and imaging of exogenous or endogenous H2S in live MCF-7 cells and in live mice with the fastest response.