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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：生物工程学院
学科：生物化工. 生物工程与技术. 药物工程
办公地点：生物楼512
联系方式：wangjingyun67@dlut.edu.cn
电子邮箱：wangjingyun67@dlut.edu.cn
扫描关注
Preparation and folic acid conjugation of fluorescent polymer nanoparticles for cancer cell targeting
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论文类型：期刊论文
发表时间：2012-08-21
发表刊物：JOURNAL OF MATERIALS CHEMISTRY
收录刊物：SCIE、EI、Scopus
卷号：22
期号：31
页面范围：16078-16083
ISSN号：0959-9428
摘要：Fluorescent polymer nanoparticles have been prepared by emulsion polymerization with a polymerisable anthrapyridone dye. This connects covalently to the polymer chains, preventing dye leakage. Amino groups were introduced into the nanoparticles by grafting with PEI (polyethyleneimine), following which folic acid was attached to the amino groups to permit targeting of certain cancer cell lines which express high levels of folate receptor.