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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：加拿大萨斯卡彻温大学
学位：博士
所在单位：生物工程学院
电子邮箱：xyping@dlut.edu.cn
扫描关注
Terminal alkyne substituted O-6-benzylguanine for versatile and effective syntheses of fluorescent labels to genetically encoded SNAP-tags
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论文类型：期刊论文
发表时间：2015-02-26
发表刊物：RSC ADVANCES
收录刊物：SCIE、EI、Scopus
卷号：5
期号：30
页面范围：23646-23649
ISSN号：2046-2069
摘要：We have developed a terminal alkyne substituted O6-benzylguanine, named PYBG, as a versatile precursor to be facilely conjugated with various fluorescent dyes through 'Click chemistry' and Sonogashira coupling reactions. These fluorescent PYBG derivatives specifically and efficiently label the target genetically encoded SNAP-tags in live cells.