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A New Highly Sensitive and Colorimetric pH Indicator Derived from 2-Amino-5-nitrothiazole and H-acid

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Indexed by:期刊论文

Date of Publication:2016-04-05

Journal:CHEMISTRY LETTERS

Included Journals:SCIE

Volume:45

Issue:4

Page Number:472-474

ISSN No.:0366-7022

Key Words:pH indicator; Naked eye; Thiazole-containing dye

Abstract:A new pH indicator having high sensitivity and significant color change visible to the naked eye from red to blue in a narrow pH range (3.2-4.0) with high molar absorption coefficient was designed and synthesized from 2-amino-5-nitrothiazole and H-acid. The possible mechanism of the indicator was proposed by H-1 NMR and C-13 NMR titration experiments. This pH indicator was successfully applied in visualization of simulated gastric fluid acid pH changes in the simulated curing process of gastric ulcer.

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