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Indexed by:期刊论文

Date of Publication:2016-06-01

Journal:TETRAHEDRON-ASYMMETRY

Included Journals:SCIE

Volume:27

Issue:9-10

Page Number:436-441

ISSN No.:0957-4166

Abstract:An asymmetric fluorination process of 4-substituted pyrazolones catalyzed by quinine is revealed. The reaction afforded a wide range of 4-fluorinated pyrazol-5-ones with excellent yields (up to 98%) and moderate to good enantioselectivities (up to 81% ee). (C) 2016 Elsevier Ltd. All rights reserved.