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Indexed by:期刊论文

Date of Publication:2016-01-01

Journal:ARKIVOC

Included Journals:SCIE

Page Number:306-327

ISSN No.:1551-7004

Key Words:Suzuki coupling; ligand-free palladium catalysis; metallocenes; polymerization

Abstract:Strategically substituted indene derivatives are useful building blocks for high efficiency olefin polymerization metallocene catalysts. In this paper, various 4-aryl-substituted 2-methyl-1H-indanones were prepared efficiently using a ligand-free palladium-catalysed Suzuki coupling procedure. Quantitative yields of indanone intermediates were achieved for most of the non-coordinative substrates with a loading of 0.005 mol% of palladium catalyst. The corresponding indene derivatives were obtained in high purity and multi-gram scale in excellent yields, following a simple sequential reduction and dehydration procedure.