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Indexed by:Journal Papers

Date of Publication:2016-01-01

Journal:ARKIVOC

Included Journals:SCIE

Page Number:110-124

ISSN No.:1551-7004

Key Words:Phenanthridines; thiols; isocyanides; cyclization; radical reactions

Abstract:An efficient method for the synthesis of 6-(arylthio)phenanthridines by tert-butyl peroxybenzoate (TBPB)-promoted cyclization reaction of 2-isocyanobiphenyls with thiols is developed. A radical pathway is proposed and evidenced for the reaction mechanism. It tolerates a wide range of substrates and represents a practical approach to 6-arylthiophenanthridines.