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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
扫描关注
C6' steric bulk of cinchona alkaloid enables an enantioselective Michael addition/annulation sequence toward pyranopyrazoles.
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论文类型：期刊论文
发表时间：2018-02-25
发表刊物：Chemical communications (Cambridge, England)
收录刊物：SCIE
卷号：54
期号：16
页面范围：2028-2031
ISSN号：1364-548X
摘要：A catalytic asymmetric Michael addition/annulation process between pyrazolones and enynones towards enantioenriched pyranopyrazoles was developed. Key features include the development of a cinchona alkaloid with C6' steric bulk as a competent catalyst and the observation of a unique stereospecific deuteration alpha to the keto group via a conducted tour pathway.