个人信息Personal Information
教授
博士生导师
硕士生导师
性别:男
毕业院校:日本东京大学
学位:博士
所在单位:化工学院
电子邮箱:qujp@dlut.edu.cn
Synthesis of aryl-substituted indanones and indenes via a highly efficient ligand-free palladium-catalyzed Suzuki coupling process
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论文类型:期刊论文
发表时间:2016-01-01
发表刊物:ARKIVOC
收录刊物:SCIE
页面范围:306-327
ISSN号:1551-7004
关键字:Suzuki coupling; ligand-free palladium catalysis; metallocenes; polymerization
摘要:Strategically substituted indene derivatives are useful building blocks for high efficiency olefin polymerization metallocene catalysts. In this paper, various 4-aryl-substituted 2-methyl-1H-indanones were prepared efficiently using a ligand-free palladium-catalysed Suzuki coupling procedure. Quantitative yields of indanone intermediates were achieved for most of the non-coordinative substrates with a loading of 0.005 mol% of palladium catalyst. The corresponding indene derivatives were obtained in high purity and multi-gram scale in excellent yields, following a simple sequential reduction and dehydration procedure.