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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
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Organocatalytic Asymmetric Fluorination of 4-Substituted Isoxazolinones
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论文类型：期刊论文
发表时间：2015-04-01
发表刊物：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
收录刊物：SCIE、Scopus
卷号：2015
期号：10
页面范围：2143-2147
ISSN号：1434-193X
关键字：Isoxazolinone; Organocatalysis; Cinchona alkaloid; Fluorine; Heterocycles
摘要：A straightforward method for the asymmetric fluorination of 4-substituted isoxazolinones catalyzed by a bis-cinchona alkaloid catalyst was developed. A series of 4-fluoroisoxazolinone derivatives with a fluorine-containing quaternary stereocenter were obtained in good to high yields with good enantioselectivities (up to 91% yield, 85% ee).