Copper-Catalyzed Aza-Diels-Alder Reaction and Halogenation: An Approach To Synthesize 7-Halogenated Chromenoquinolines
Release Time:2019-03-13 Hits:
Indexed by: Journal Article
Date of Publication: 2016-05-20
Journal: ORGANIC LETTERS
Included Journals: PubMed、SCIE
Volume: 18
Issue: 10
Page Number: 2491-2494
ISSN: 1523-7060
Abstract: A new halogenation method to construct halogen-substituted quinoline moieties is described. The Cu-catalyzed intramolecular aza-Diels-Alder reaction and halogenation reaction proceeded smoothly under mild conditions to produce the corresponding 7-chloro-6H-chromeno[4,3-b]quinolines and 7-chloro-6H-thiochromend[4,3-b]quinolines in satisfactory yields.