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Copper-Catalyzed Aza-Diels-Alder Reaction and Halogenation: An Approach To Synthesize 7-Halogenated Chromenoquinolines

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Indexed by:期刊论文

Date of Publication:2016-05-20

Journal:ORGANIC LETTERS

Included Journals:SCIE、PubMed

Volume:18

Issue:10

Page Number:2491-2494

ISSN No.:1523-7060

Abstract:A new halogenation method to construct halogen-substituted quinoline moieties is described. The Cu-catalyzed intramolecular aza-Diels-Alder reaction and halogenation reaction proceeded smoothly under mild conditions to produce the corresponding 7-chloro-6H-chromeno[4,3-b]quinolines and 7-chloro-6H-thiochromend[4,3-b]quinolines in satisfactory yields.

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