Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-02-15

Journal: JOURNAL OF ORGANIC CHEMISTRY

Included Journals: Scopus、PubMed、EI、SCIE

Volume: 78

Issue: 4

Page Number: 1693-1698

ISSN: 0022-3263

Abstract: An efficient method for the synthesis of 3,5-disubstituted pyrazoles is described. The reactions of 1,3-dialkynes with hydrazine proceeded smoothly in dimethyl sulfoxide under mild reaction conditions to produce 3,5-disubstituted pyrazoles in satisfactory to excellent yields. A one-pot procedure of the transformation has been developed.