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论文类型：期刊论文

发表时间：2019-10-01

发表刊物：SENSORS AND ACTUATORS B-CHEMICAL

收录刊物：SCIE、EI

卷号：296

ISSN号：0925-4005

关键字：Plasmonic probe; Adenosine detection; Gold nanoparticle; Eyedropper function; Colorimetric assay

摘要：Adenosine, as an endogenous molecule in organisms, plays an essential role in biological processes. Here, a plasmonic probe, creatinine-Ag+/gold nanoparticle (AuNPs), is assembled for adenosine detection based on synergistic coordination on AuNPs. The A(650 nm/520 nm) values of AuNPs system change linearly with adenosine concentration over a range of 1.0-5.0 mu M and the detection limits reached 45 nM. The adenosine detection is realized within 4 min. Furthermore, the quantitative detection of adenosine is realized by eyedropper (a function in Microsoft's PowerPoint) for analyzing RGB value changes of colorimetric assay. Therefore, this sensor can provide accurate and rapid assay of adenosine in patients' serum sample without complicated instrumentations.