郭慧敏

个人信息Personal Information

副教授

硕士生导师

性别:女

毕业院校:Regensburg大学

学位:博士

所在单位:化学学院

学科:分析化学

电子邮箱:guohm@dlut.edu.cn

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Enantioselective Recognition of Tartaric Acids with Ethynylated Carbazole-Based Chiral Bisboronic Acid Chemosensors with Improved Response at Acidic pH

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论文类型:期刊论文

发表时间:2011-09-01

发表刊物:JOURNAL OF FLUORESCENCE

收录刊物:Scopus、SCIE、EI、PubMed

卷号:21

期号:5

页面范围:1979-1986

ISSN号:1053-0509

关键字:Chiral boronic acid; Enantioselective; Fluorescent chemosensors; Tartaric acid; PET

摘要:Chiral bisboronic acid chemosensors based on ethynylated carbazole were prepared. The chiral chemosensors show red-shifted emission than the chemosensors with unsubstituted carbazole fluorophore. a-PET effect was found for the chemosensors, which is different from our previous observation of the d-PET effect for boronic acid chemosensors based on carbazole. Enantioselective recognition of tartaric acids was implicated with these chemosensors. Consecutive fluorescence emission enhancement/diminishment were observed with increasing the concentration of the tartaric acids, which is tentatively assigned to the transition of the binding stoichiometry from 1:1 binding to 1:2 binding. In particularly interesting is the improved fluorescence response at acidic pH for recognition of tartaric acids, which is rarely observed for a-PET chemosensors. We propose that the sensing is due to hybrid mechanism of a-PET/d-PET and conformational restriction upon binding. Our results will be useful for design of chiral boronic acid chemosensors with improved fluorescence response at acidic pH, which are rarely reported.