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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：南京大学
学位：博士
所在单位：化工学院
电子邮箱：hecheng@dlut.edu.cn
A FRET approach for luminescence sensing Cr3+ in aqueous solution and living cells through functionalizing glutathione and glucose moieties
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论文类型：期刊论文
发表时间：2011-02-11
发表刊物：TETRAHEDRON
收录刊物：Scopus、SCIE
卷号：67
期号：6
页面范围：1091-1095
ISSN号：0040-4020
关键字：Chemosensor; Cr3+; Glucose tolerance factors; FRET
摘要：A simple FRET-based approach to ratiometric fluorescence sensing of Cr3+ in aqueous solution using glutathione and glucose as building blocks was achieved, inspired to the binding motifs of Cr3+ in glucose tolerance factors (GTF). Selectivity and competition experiments showed that this system featured high sensitivity (detection limit <= 0.1 ppm) and excellent selectivity over other metal ions in buffer solution. Confocal fluorescence microscopy experiments had established the utility of the approach in monitoring Cr3+ within living cells. (C) 2010 Elsevier Ltd. All rights reserved.