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Aβ聚集的影响因素和Aβ寡聚体的生理功能

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Indexed by:期刊论文

Date of Publication:2012-09-10

Journal:中国老年学杂志

Included Journals:PKU、ISTIC

Volume:32

Issue:17

Page Number:3848-3850

ISSN No.:1005-9202

Key Words:阿尔茨海默病;Aβ;Aβ聚集

Abstract:阿尔茨海默病(AD)俗称老年痴呆症,分为家族型AD和年龄依赖型AD,以后者为主,主要发病年龄在60~65岁以上.我国具有庞大的人口基数,随着老龄化社会的到来,明确AD的生理病理机制变化越来越重要.多年的研究表明大脑内的淀粉样β肽(Aβ)在AD的发生发展中起重要作用.

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