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微通道壁面突起对片上电泳分离流动特性影响数值计算研究

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Indexed by:期刊论文

Date of Publication:2022-06-30

Journal:计算力学学报

Affiliation of Author(s):机械工程学院

Issue:1

Page Number:25-29

ISSN No.:1007-4708

Abstract:Numerical simulation and theoretical analysis are developed on the effect of protuberances to electrophoresis separation in micro-channel. The reasons for forming protuberances on a micro-channel surface and their effect on electrophoresis separation are analyzed. The physics governing equations and the discrete formations for capillary electrophoresis separation are presented too. The program of numerical simulation for electrophoresis separation is developed, in which the distribution of electric field, electroosmotic velocity and concentration of species are simulated with finite volume method. The effects of structural parameters for protuberances on electrophoresis separation are described. According to the results the height of protuberances is critical for electrophoresis separation, as ratio of protuberances height to micro-channel width increases from 0 to 0.2, the velocity of electroosmotic flow decreases about 20%.

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