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Versatile acenaphtho[1,2-b]pyrrol-carbonitriles as a new family of heterocycles: diverse Snar(H)H reactions, cytotoxicity and spectral behavior

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Indexed by:期刊论文

Date of Publication:2005-11-21

Journal:TETRAHEDRON

Included Journals:SCIE

Volume:61

Issue:47

Page Number:11264-11269

ISSN No.:0040-4020

Key Words:SNArH reaction; nucleophiles; acenaphtho-heterocycles

Abstract:The diverse reactivity of highly electron-deficient 8-oxo-8H-acenaphtho[1,2-b]pyrrol-9-carbonitrile I is attractive for the preparation of derivatives bearing different substituents via SNArH reaction with N, O, S nucleophiles. These derivatives were versatile, possessing potential antitumor activities and displaying tunable fluorescence spectral behavior. (c) 2005 Published by Elsevier Ltd.

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