Current position: Home >> Scientific Research >> Paper Publications

Novel fluorescent pH sensors based on intramolecular hydrogen bonding ability of naphthalimide

Release Time:2019-11-01  Hits:

Indexed by: Journal Article

Date of Publication: 2004-08-05

Journal: ORGANIC LETTERS

Included Journals: PubMed、SCIE

Volume: 6

Issue: 16

Page Number: 2757-2760

ISSN: 1523-7060

Abstract: 4-Piperidine-naphthalimide derivatives containing potential acceptors for hydrogen bonding were synthesized, and their fluorescence properties were examined. Some of the compounds with a 2-imino-oxalidin (thiazolidin) side chain at the imide moiety exhibit a strong fluorescence quench and some red shift in weakly acidic conditions, caused by the formation of an intramolecular hydrogen bond. Their pK(a), values were estimated to be about 6.4-7.5. The results showed that these compounds could serve as novel fluorescent pH sensors for further application.

Prev One:Novel naphthalimide fluorescent sensors selective for certain proteins on basis of non-covalent interactions between enzyme and inhibitor

Next One:Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: Various DNA binding geometry and interesting antitumor capacity