吴硕

个人信息Personal Information

教授

博士生导师

硕士生导师

主要任职:化学学院副院长

其他任职:辽宁省教学名师,宝钢优秀教师特等奖提名奖,中国分析测试学会青年学术委员会委员

性别:女

毕业院校:南京大学

学位:博士

所在单位:化学学院

学科:分析化学. 生物化学与分子生物学

办公地点:化工综合楼C305

电子邮箱:wushuo@dlut.edu.cn

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Development of Triphenylamine Functional Dye for Selective Photoelectrochemical Sensing of Cysteine

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论文类型:期刊论文

发表时间:2014-06-17

发表刊物:ANALYTICAL CHEMISTRY

收录刊物:SCIE、EI、PubMed、Scopus

卷号:86

期号:12

页面范围:5922-5928

ISSN号:0003-2700

摘要:A novel triphenylamine-based organic dye, TTA, with an acrylic group is designed to graft TiO2 nanoparticles for sensitive and selective photoelectrochemical sensing. The synthesized TTA possesses a high molar absorption coefficient, leading to an enhanced photoelectron emission ability of the electron donor. The carboxyl group of TTA acts as not only an electron acceptor but also a linker to connect TTA to TiO2 nanoparticles. Under irradiation, TTA shows fast intramolecular charge transfer from triphenylamine to carboxyl group via the pi-bridge of thiophene moiety, thus producing a sensitive photocurrent response. Meanwhile, the acrylic moiety provides an active site for the Michael addition reaction, which would destroy the pi-bridge and decrease the photocurrent response. Thus, a selective photoelectrochemical sensing strategy is proposed for detection of small biomolecules. Using cysteine as a model analyte, this sensing strategy shows a detectable range from 1 to 200 mu M, without the interference from natural amino acids and various biological reducing reagents. This work offers a new photoelectrochemical route to highly selective and sensitive detection of biologically important small molecules.