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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：兰州大学
学位：博士
所在单位：化工学院
学科：有机化学. 药物化学. 精细化工
办公地点：西部校区化工实验楼G-413
联系方式：0411-84986190 15942819406
电子邮箱：bmwang@dlut.edu.cn
扫描关注
Construction of indolenine-substituted spiro[pyrrolidine-2,3 '-oxindoles] from 2-alkenylindolenines and isatin-derived azomethine ylides
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论文类型：期刊论文
发表时间：2018-05-10
发表刊物：TETRAHEDRON
收录刊物：SCIE
卷号：74
期号：19
页面范围：2369-2375
ISSN号：0040-4020
关键字：Spirooxindole; Indolenine; 1,3-Dipolar cycloaddition; Azomethine ylide; Regioselectivity
摘要：An organic base-catalyzed 1,3-dipolar cycloaddition between 2-alkenylindolenines and azomethine ylides derived from isatins and benzylamines was successfully developed to assemble indolenine-substituted spiro [pyrrolidine-2,3'-oxindole] ring systems. Generally, good regioselectivities (up to 14:1 rr) and high yields (up to 91%) were obtained under mild conditions. (C) 2018 Elsevier Ltd. All rights reserved.