王保民

个人信息Personal Information

教授

博士生导师

硕士生导师

性别:男

毕业院校:兰州大学

学位:博士

所在单位:化工学院

学科:有机化学. 药物化学. 精细化工

办公地点:西部校区化工实验楼G-413

联系方式:0411-84986190 15942819406

电子邮箱:bmwang@dlut.edu.cn

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Substrate-controlled divergent synthesis of polycyclic indoloazepines and indolodiazepines via 1,5-hydride shift/7-cyclization cascades

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论文类型:期刊论文

发表时间:2018-07-21

发表刊物:CHEMICAL COMMUNICATIONS

收录刊物:SCIE

卷号:54

期号:57

页面范围:7928-7931

ISSN号:1359-7345

摘要:Novel and practical acid-catalyzed cyclization of 2-indolyl aryl carbinols via tandem dehydration/1,5-hydride shift/7-cyclization sequences has been developed. By appropriate variation of the substrate, diverse polycyclic-fused indoles were synthesized in good yield, thus demonstrating the high efficiency, transition-metal-free nature, and high step/atom economy of the synthesis strategy.