王保民
个人信息Personal Information
教授
博士生导师
硕士生导师
性别:男
毕业院校:兰州大学
学位:博士
所在单位:化工学院
学科:有机化学. 药物化学. 精细化工
办公地点:西部校区化工实验楼G-413
联系方式:0411-84986190 15942819406
电子邮箱:bmwang@dlut.edu.cn
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Substrate-controlled divergent synthesis of polycyclic indoloazepines and indolodiazepines via 1,5-hydride shift/7-cyclization cascades
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论文类型:期刊论文
发表时间:2018-07-21
发表刊物:CHEMICAL COMMUNICATIONS
收录刊物:SCIE
卷号:54
期号:57
页面范围:7928-7931
ISSN号:1359-7345
摘要:Novel and practical acid-catalyzed cyclization of 2-indolyl aryl carbinols via tandem dehydration/1,5-hydride shift/7-cyclization sequences has been developed. By appropriate variation of the substrate, diverse polycyclic-fused indoles were synthesized in good yield, thus demonstrating the high efficiency, transition-metal-free nature, and high step/atom economy of the synthesis strategy.