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Indexed by:期刊论文

Date of Publication:2018-01-05

Journal:Environmental science and pollution research international

Included Journals:SCIE

Volume:25

Issue:8

Page Number:8035-8043

ISSN No.:1614-7499

Key Words:Cultured fish,Fluoroquinolones,Risk assessment,Tetracyclines

Abstract:Occurrence and levels of 11 fluoroquinolones (FQs) and four tetracyclines (TC) in 14 cultured fish species from a coastal city in the northern China were investigated. Five FQs (ofloxacin, enoxacin, ciprofloxacin, enrofloxacin, and sarafloxacin) and oxytetracycline were detected. Lower detection frequencies of antibiotics were observed in the marine fish. The concentrations of SigmaFQs ranged from not detectable (nd) to 130ng/g wet weight (ww) (median, 7.2ng/g ww), and the concentration range of SigmaTCs was nd to 200ng/g ww (median, nd ng/g ww). The Chinese snakehead contained the highest concentrations of SigmaFQs (130ng/g ww) and the small yellow croaker accumulated the highest concentrations of SigmaTCs (200ng/g ww), respectively. Although the calculated estimated daily intakes (EDI) suggested that the consumption of these cultured fish from this region was not associated with significant human health risks, this study provides useful information that will be helpful in the appropriate antibiotic use in aquaculture. To our knowledge, this can be the first report on the occurrence and levels of antibiotics in cage-cultured marine fish from the Bohai Rim region, China.