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论文类型：期刊论文

发表时间：2018-11-01

发表刊物：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

收录刊物：PubMed、SCIE、Scopus

卷号：25

期号：32

页面范围：32081-32087

ISSN号：0944-1344

关键字：Sulfonamides; Macrolides; Fluoroquinolones; Sea cucumber; Occurrence; Risk assessment

摘要：Occurrence and distribution of 24 antibiotics from 7 categories were screened in sea cucumbers (Echinodermata: Holothuroidea) collected from different coastal regions of China. The samples were simultaneously extracted and purified using accelerated solvent extraction with in-cell clean-up and analyzed by ultra-performance liquid chromatography-tandem mass spectrometry. A total of ten antibiotics were detected in the sea cucumbers with concentrations ranging from not detected to 32.8g/kg (dry weight). Sulfonamides are predominant antibiotics with a mean concentration of 11.5g/kg (dry weight), followed by macrolides (11.3g/kg, dry weight) and fluoroquinolones (11.2g/kg, dry weight). High concentrations of the antibiotics were found in the samples from the South China Sea, implying that the antibiotic pollution in sea cucumbers was geographical region-dependent, which was further confirmed by principal component analysis. It was also found that the antibiotic levels are slightly higher in instant sea cucumbers than in the dried ones. Hazard quotient calculation suggested no obvious human health risks associated with the consumption of sea cucumbers regarding antibiotics.