赵洪霞

  • 教授     博士生导师   硕士生导师
  • 性别:女
  • 毕业院校:中国科学院大连化学物理研究所
  • 学位:博士
  • 所在单位:环境学院
  • 学科:环境科学. 环境工程
  • 办公地点:环境楼B709
  • 联系方式:hxzhao@dlut.edu.cn
  • 电子邮箱:hxzhao@dlut.edu.cn

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Presence and environmental risk assessment of selected antibiotics in coastal water adjacent to mariculture areas in the Bohai Sea

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论文类型:期刊论文

发表时间:2019-08-15

发表刊物:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

收录刊物:PubMed、SCIE

卷号:177

页面范围:117-123

ISSN号:0147-6513

关键字:Antibiotics; Bohai sea; Coastal water; Mariculture areas; Risk assessment

摘要:The presence and concentrations of 25 antibiotics in Dalian coastal water of the Bohai Sea were investigated using solid-phase extraction coupled with high-performance liquid chromatography tandem mass spectrometry. Results showed that antibiotics were widely detected in this region with total concentration ranging from 22.6 to 2402.4 ng/L. Enrofloxacin and trimethoprim were 100% detected followed by sulfamethoxazole with a detection rate of 90.9%. No significant correlations were found between antibiotics concentrations and sample parameters such as dissolved organic carbon, salinity, and distance from the coast, suggesting that concentrations and distributions of the antibiotics in this area were source-dependent. Antibiotic concentration in the sample from an offshore cage-culture area was the highest. Based on composition profiles, mariculture was supposed to be an important source of antibiotics. According to the assessment, individual antibiotic posed low to moderate risk, while the antibiotic mixture presented high risk. Enrofloxacin, clarithromycin and sulfamethoxazole, the top three contributors to the mixture risk quotients for each site, need priority control in this area. Besides, levels of enrofloxacin were high enough to exert a selective pressure on bacteria that may lead to an increase in the prevalence of resistance.