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发表时间：2015-01-01

发表刊物：大连医科大学学报

期号：4

页面范围：324-327

ISSN号：1671-7295

摘要：Objective To establish a macro-biomechanical model of the guinea pig's cochlea.Methods Both cochlea, abstracted from bilateral temporal bones of a healthy adult guinea pig, which was tested firstly including a series of examina-tion including electric otoscopy, acoustic immittance,brainstem auditory evoked potential, otoacoustic emissions, CT scan and so on.And then, a whole set of inner ear tissue slices images was obtained after a series of operations including embed-ding, slicing ( thickness 6μm) , immobilization, coloretur, photographing and so on.The images were processed by Photo-shop software, mimics software and Hypermesh software sequencely and a biomechanical model of the cochlea was obtained with ANSYS13.0 eventually.Based on the model, the modal analysis was done to test the accuracy of the model.Results Spatial structural feature of the reconstructed biomechanical model of the guinea pig's cochlea was displayed typically and the result of the model analysis proceeded on the macro-biomechanical model was the same as traveling wave theory.Con-clusion It is feasible technically to reconstruct biomechanical model of the cochlea with the tissue slices combining with the finite element soft wares.And the macro-biomechanical model could be applied to study the sensing process of cochlea.

备注：新增回溯数据