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发表时间：2015-01-01

发表刊物：力学学报

卷号：47

期号：6

页面范围：1065-1072

ISSN号：0459-1879

摘要：The vestibular system, the most important organ to maintain the human
   body balance, involves three systems, including the vestibular, visual
   and proprioception. Because of its fine structure and deep location of
   the vestibule and the three semicircular canals, the traditional method
   was difficult to meet the positioning, qualitative and quantitative
   research of modern vestibular medicine, while biological numerical
   simulation has the advantages in modern otology, in which it is
   important to establish an accurate biological numerical model. Based on
   two-dimensional anatomical data of guinea pig inner ear by serial tissue
   sections, three-dimensional biological numerical model of the vestibular
   system containing the vestibule and the three semicircular canals was
   established and the spatial structure and size of the model was
   consistent with the anatomic observation. Furthermore, numerical
   simulation of the caloric test was carried out on the model and
   biomechanical characteristics of top of semicircular canal crest were
   described quantitatively with the parameters including displacement,
   velocity and pressure under the different environment temperature
   excitation and the results were in agreement with the clinical
   observation. In short, it was feasible to reconstruct a biological
   numerical model of the vestibular system based on the two-dimensional
   anatomical data by continuous tissue slicing technique and the
   biological model meets the needs of positioning, qualitative and
   quantitative research of the vestibular and semicircular canals balance
   function.

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