个人信息Personal Information
副教授
博士生导师
硕士生导师
性别:女
毕业院校:大连理工大学
学位:博士
所在单位:创新创业学院
学科:应用数学
办公地点:创新创业学院602
联系方式:84707445-6602
电子邮箱:qhpan@dlut.edu.cn
A new graphical representation of protein sequences and its applications
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论文类型:期刊论文
发表时间:2016-02-15
发表刊物:PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
收录刊物:SCIE、EI、Scopus
卷号:444
页面范围:996-1002
ISSN号:0378-4371
关键字:Sequences analysis; Similarity; Moments of inertia; Tensor; Phylogenetic tree
摘要:Sequence analysis is one of the foundations in bioinformatics for the abundant information hidden in the sequences. It is helpful for scientists' study on the function of DNA, proteins and cells. In this paper, we outline a novel method for protein sequences similarity analysis based on the physical-chemical properties of amino acids. We consider the protein sequence as a rigid-body with mass. Then we introduce the moment of inertia to the calculation of similarity of sequences and the sequences are transformed into vectors by the tensor for moment of inertia. The Euclidean distance is employed as a measurement of the similarities. At last, the comparison with other references' results shows our approach is reasonable and effective. (C) 2015 Elsevier B.V. All rights reserved.