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Bronsted acid-catalyzed metal- and solvent-free quinoline synthesis from N-alkyl anilines and alkynes or alkenes

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Indexed by:期刊论文

Date of Publication:2018-01-07

Journal:GREEN CHEMISTRY

Included Journals:SCIE

Volume:20

Issue:1

Page Number:261-265

ISSN No.:1463-9262

Abstract:Bronsted acid-catalyzed cyclization reactions of N-alkyl anilines with alkynes or alkenes in the presence of oxygen gas as an oxidant under metal- and solvent-free conditions are described. Various quinoline derivatives are obtained in satisfactory to excellent yields. Different groups, such as methyl, fluoro, chloro, bromo, methoxy, and ester linked on benzene rings, are tolerated under optimized reaction conditions.

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