Current position: Home >> Scientific Research >> Paper Publications

Arylglycine-derivative synthesis via oxidative sp(3) C-H functionalization of alpha-amino esters

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-09-18

Journal: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

Included Journals: Scopus、PubMed、SCIE

Volume: 8

Page Number: 1564-1568

ISSN: 1860-5397

Key Words: alpha-amino ester; arylglycine; C-H functionalization; oxidation; synthesis

Abstract: An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with alpha-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields.

Prev One:Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

Next One:Oxidative Coupling of Indoles with Ethyl 2-(Disubstituted Amino)Acetates: An Approach to Achieve Indolylglycine Derivatives