location: Current position: Home >> Scientific Research >> Paper Publications

Arylglycine-derivative synthesis via oxidative sp(3) C-H functionalization of alpha-amino esters

Hits:

Indexed by:期刊论文

Date of Publication:2012-09-18

Journal:BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY

Included Journals:SCIE、PubMed、Scopus

Volume:8

Page Number:1564-1568

ISSN No.:1860-5397

Key Words:alpha-amino ester; arylglycine; C-H functionalization; oxidation; synthesis

Abstract:An efficient method for the synthesis of arylglycine derivatives is described. The oxidative coupling reactions of naphthols and phenols with alpha-amino esters proceeded smoothly in the presence of meta-chloroperoxybenzoic acid as an oxidant under ambient conditions, to produce arylglycine derivatives in satisfactory yields.

Pre One:Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

Next One:Oxidative Coupling of Indoles with Ethyl 2-(Disubstituted Amino)Acetates: An Approach to Achieve Indolylglycine Derivatives