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Copper-catalyzed conversion of aryl and heteroaryl bromides into the corresponding chlorides

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-10-04

Journal: CHEMICAL COMMUNICATIONS

Included Journals: Scopus、PubMed、SCIE

Volume: 48

Issue: 76

Page Number: 9468-9470

ISSN: 1359-7345

Abstract: An efficient method for the synthesis of aryl and heteroaryl chlorides is described. The reactions of aryl and heteroaryl bromides with tetramethylammonium chloride proceeded smoothly in the presence of a copper catalyst under mild reaction conditions to produce the corresponding chlorides in satisfactory to excellent yields.

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