Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-07-01

Journal: SYNLETT

Included Journals: Scopus、SCIE

Volume: 23

Issue: 11

Page Number: 1605-1608

ISSN: 0936-5214

Key Words: palladium catalyst; direct conjugate addition; heteroarene; unsaturated ketone; C-H activation

Abstract: Palladium-catalyzed direct conjugate additions of heteroarenes to alpha,beta-unsaturated ketones via C-H activation are described. The reactions of heteroarenes with alpha,beta-unsaturated ketones proceeded smoothly in the presence of PdCl2 as a catalyst under mild conditions to give the corresponding Michael adducts in moderate to excellent yields.