Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-05-04

Journal: ORGANIC LETTERS

Included Journals: Scopus、PubMed、SCIE

Volume: 14

Issue: 9

Page Number: 2418-2421

ISSN: 1523-7060

Abstract: An efficient method for the synthesis of 3,5-disubstituted Isoxazoles is described. The reactions of 1,3-dialkynes with hydroxylamine proceeded smoothly in DMSO under mild reaction conditions to produce 3,5-disubstituted isoxazoles In satisfactory to excellent yields.