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Indexed by:会议论文

Date of Publication:2016-03-21

Included Journals:EI、CPCI-S、Scopus

Volume:9802

Key Words:Portable microscope platform; Pixel super-resolution; SqCC; Telemedicine; Red tide

Abstract:Light microscopy can not only address various diagnosis needs such as aquatic parasites and bacteria such as E. coli in water, but also provide a method for the screening of red tide. Traditional microscope based on the smartphone created by adding lens couldn't keep the tradeoff between field-of-view(FOV) and the resolution. In this paper, we demonstrate a non-contact, light and cost-effective microscope platform, that can image highly dense samples with a spatial resolution of similar to 0.8um over a field-of-view(FOV) of >1mm(2). After captured the direct images, we performed the pixel super-resolution algorithm to improve the image resolution and overcome the hardware interference. The system would be a good point-of-care diagnostic solution in resource limited settings. We validated the performance of the system by imaging resolution test targets, the squamous cell cancer(SqCC) and green algae that necessary to detect the squamous carcinoma and red tide