孙亮
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论文类型:会议论文
发表时间:2017-01-01
收录刊物:CPCI-S
卷号:2017-January
页面范围:2241-2243
关键字:motif recognition; random projection; particle swarm optimization
摘要:Motif recognition plays a significant role for understanding the biological meanings of sequences. In this paper, a particle swarm optimization and random projection based algorithm (PSORPS) is proposed for recognizing DNA motifs. First, noise subsequences are filtered by a random projection strategy for constructing objective space. Then the PSO is used to automatically search the motifs of DNA sequences in the constructed l-mer objective space. Finally, the operators of independent drift and associated drift are conducted on the optimization results to alleviate base deviation. The experiments are carried out on real-world biological datasets, and the results validate the effectiveness of the proposed algorithm.